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’ refers to designer cannabinoids such as JWH-018, JWH-073, JWH-200 and (C8)-CP 47,497, initially found in ‘herbal smoking blends’; these are sold under many names, including K2, fake weed, Yucatan fire, skunk, moon rocks and others.

Synthetic cannabinoid agonists, including RCS-4, RCS-8 and AB-001, are also available.

Go on missions and complete quests or just play around in this massive open world game.Sometimes marketed as ‘plant food’, ‘jewellery cleaner’ or ‘phone screen cleaner’, they are sold online under a variety of names, such as K4 rage, cloud nine, ocean snow, ivory wave, sextacy ultra, white rush, white lightning, bloom, lunar wave, vanilla sky and scarface.Bath salts are typically taken orally, smoked, inhaled or injected – the worst outcomes being after snorting or injection.Designer analogues of sildenafil (Viagra) have been used as active compounds in ‘herbal’ aphrodisiac products.One unique aspect of the “Spice” phenomenon is that the constituents of “Spice” are changing over time.As first observed in the UK (), as these compounds were banned, they were replaced by structurally similar and pharmacologically active compounds that skirted the regulations. While the specific combination of synthetic cannabinoids in “Spice” may change over time, the primary site and mechanism of action of its components remains unchanged.

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